Menu
Home
Forum Rules
Store
Donate
Meltdown Mayhem Hacks ⚔︎
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
Log in
Register
What's new
Menu
Log in
Register
Home
Sweatshop - Pure Drama
Political Fray
Kookie Kennedy to replace vaccine scientists from the vaccine advisory board, with essential oil sales representatives
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Holy Holliday !" data-source="post: 1422604" data-attributes="member: 13772"><p>I recall hearing of this. Even if it does, for reasons hypothesized below, it is not 100% and the overall health risked outweigh the benefits. Further there is no conclusive evidence that it is protective as some thought.</p><p></p><h2><strong>A pack of Gauloises a day keeps the doctor away?</strong></h2><p>The nicotinic hypothesis was formulated quickly: a month after our own university moved to working from home, a group in Paris proposed their theory in a <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.5802%2Fcrbiol.8&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216729710%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=1bLEBTeLn7yNS38vrM0qgf8h0GXcII2%2F8T3ui56YTN4%3D&reserved=0" target="_blank">manuscript</a></u> promptly published in <em>Comptes Rendus Biologies. </em>At the time, it looked as if smokers were protected from the infection. In <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.toxrep.2020.04.012&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216753427%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=FZzEKEuUPkVw7nSrVk1oVFo8TTUfZ6slbQ5aCKhA%2FYE%3D&reserved=0" target="_blank">studies coming out of China</a></u>, smokers were <em>underrepresented </em>in patients hospitalized with the new disease. Doctors were seeing fewer of them than they would expect based on the percentage of the population that smokes—and on the fact that smoking generally predisposes you to a number of respiratory infections, including <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.jinf.2019.08.014&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216776376%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=FZdSf50scupye5i0eb2qlNpYVVGFJyWbT5p%2FPvyfvQ4%3D&reserved=0" target="_blank">the flu</a></u>, <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1186%2F1617-9625-4-12&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216799012%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=b00X24%2F5uHZw2Ot4dji2uvSQ9BKZzN8zL0Gn2E0epoo%3D&reserved=0" target="_blank">tuberculosis</a></u>, and <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1056%2Fnejm200003093421002&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216817240%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=xW5yFf020MDAZzeyQRqiskuGJ6XEflvlIN2pO9N26Uk%3D&reserved=0" target="_blank">invasive pneumococcal disease</a></u>. The Parisian medical researchers wondered what could explain this.</p><p></p><p>We knew at the time that the coronavirus binds to the ACE2 receptors expressed on the outside of cells in our airways, like a key fitting into a lock. But because COVID was often accompanied by an inflammatory component, it was hypothesized that the virus could <em>also</em> bind to another type of receptor: nicotinic acetylcholine receptors or nAChRs for short. These receptors usually interact with the neurotransmitter acetylcholine, but molecules in some snake venoms and strains of the rabies virus can also bind to them because of a short sequence of amino acids. And this sequence was shared, the Parisian team found, by the spike protein that the coronavirus displayed at its surface like a crown of thorns. The new virus could thus, <em>in theory</em>, displace acetylcholine from nAChRs and cause damage.</p><p></p><p>The hypothesis went on that, because nicotine binds to these same receptors very, very strongly, smokers were protected from the more severe effects of the coronavirus. The spike protein wanted to access this lock, but nicotine keys were already jammed in there and they were in no hurry to leave. Hence the otherwise unsound proposal, in the team’s April 2020 paper, that “nicotine may be suggested as a potential preventative agent against COVID-19 infection.” French doctors were not telling their countrymen to pick up a pack of Gauloises; they highlighted that nicotine is a “drug of abuse” and that smoking is bad, but they wondered about “nicotinic agents” in controlled settings. Perhaps nicotine patches.</p><p></p><p>The scientific evidence for this hypothesis is, at this point, artificial and far from conclusive. A team has shown that, when <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.3390%2Fijms21165807&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216836362%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=EMEQ8CiinW1g4lhb5e7700iGLo9ViD%2F9yMmJS2St8aw%3D&reserved=0" target="_blank">using computers</a></u> to predict what will happen, the coronavirus’ spike protein <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.fct.2021.112009&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216857317%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=BsLGv%2Bcha5Z6h3bT8TaSjlLuTIbcUjSUd4pRx%2Fn0Hk4%3D&reserved=0" target="_blank">can bind</a></u> to these nicotinic receptors. Researchers have also forced cells in the lab (namely human kidney cells and frog egg cells) to express certain types of nicotinic receptors and put them in a solution containing a fragment of the spike protein created in the lab, and the <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1007%2Fs12035-022-02947-8&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216881283%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=aZ7wDKE%2F5Bfc3owOhj8OOrvNNCUsDGDr0yS2dJ4%2FwqI%3D&reserved=0" target="_blank">results</a></u> <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1073%2Fpnas.2204242119&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216901595%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=%2BWV8FzZ1xW2H9EQSXLeuwhX%2FFWOas09VT9QEkUxxEPM%3D&reserved=0" target="_blank">have been</a></u> <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.jbc.2023.104707&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216920808%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=wJHQSBJBN4WwbahF58HetA%2BS2MM7DDR8z7eDaFdWK%2BE%3D&reserved=0" target="_blank">contradictory</a></u>. On either side of the debate, fans can pick the papers that support their position, but what the data reveals is that if this hypothesis is indeed true, it comes with a number of caveats.</p><p></p><p><span style="color: rgb(184, 49, 47)">Speaking of caveats, those early reports that smokers were underrepresented in COVID hospital wards were <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1038%2Fs41533-021-00223-1&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216940810%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=QWwngqTmc4YcGUPBJjgJ%2Flbq1dIVYSH3CpwDi8NFeQc%3D&reserved=0" target="_blank">deeply flawed</a></u>, using data sets where the smoking status of a significant portion of hospitalized patients was missing or where people who had recently stopped smoking were categorized not as smokers but as “former smokers.”</span></p><p><span style="color: rgb(184, 49, 47)"></span></p><p><span style="color: rgb(184, 49, 47)">Oh, and the French team that proposed the nicotinic hypothesis and suggested that maybe nicotine could prevent COVID-19? Its star scientist, Jean-Pierre Changeux, received <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.lemonde.fr%2Fsciences%2Farticle%2F2012%2F05%2F31%2Fguerre-du-tabac-la-bataille-de-la-nicotine_1710837_1650684.html&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216963546%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=DfIApZFd5kGIvFZ%2BEfIWqj4k2WaDzrolfCwmzIQ0i1Y%3D&reserved=0" target="_blank">$220,000 from the tobacco industry</a></u> to fund his research in the mid-90s, according to newspaper </span><em><span style="color: rgb(184, 49, 47)">Le Monde.</span></em></p><p><em></em></p><p><em><span style="color: rgb(84, 172, 210)">Some people with long COVID report that nicotine patches <u><a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fthesicktimes.org%2F2025%2F10%2F17%2Fnicotine-patches-help-relieve-symptoms-in-some-people-with-long-covid-can-the-science-behind-it-lead-to-future-therapies%2F&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635217080665%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=bzQ74cCZWMiirbjXelDzMnpOj0N76WrHJzykrSN2N0U%3D&reserved=0" target="_blank">cleared their symptoms</a></u>, while others say their symptoms worsened. These anecdotes are not conclusive; rather, they can be hypothesis generating. In the absence of good, validated treatments for long COVID, I can understand the desire to try just about anything</span></em></p></blockquote><p></p>
[QUOTE="Holy Holliday !, post: 1422604, member: 13772"] I recall hearing of this. Even if it does, for reasons hypothesized below, it is not 100% and the overall health risked outweigh the benefits. Further there is no conclusive evidence that it is protective as some thought. [HEADING=1][B]A pack of Gauloises a day keeps the doctor away?[/B][/HEADING] The nicotinic hypothesis was formulated quickly: a month after our own university moved to working from home, a group in Paris proposed their theory in a [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.5802%2Fcrbiol.8&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216729710%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=1bLEBTeLn7yNS38vrM0qgf8h0GXcII2%2F8T3ui56YTN4%3D&reserved=0']manuscript[/URL][/U] promptly published in [I]Comptes Rendus Biologies. [/I]At the time, it looked as if smokers were protected from the infection. In [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.toxrep.2020.04.012&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216753427%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=FZzEKEuUPkVw7nSrVk1oVFo8TTUfZ6slbQ5aCKhA%2FYE%3D&reserved=0']studies coming out of China[/URL][/U], smokers were [I]underrepresented [/I]in patients hospitalized with the new disease. Doctors were seeing fewer of them than they would expect based on the percentage of the population that smokes—and on the fact that smoking generally predisposes you to a number of respiratory infections, including [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.jinf.2019.08.014&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216776376%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=FZdSf50scupye5i0eb2qlNpYVVGFJyWbT5p%2FPvyfvQ4%3D&reserved=0']the flu[/URL][/U], [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1186%2F1617-9625-4-12&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216799012%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=b00X24%2F5uHZw2Ot4dji2uvSQ9BKZzN8zL0Gn2E0epoo%3D&reserved=0']tuberculosis[/URL][/U], and [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1056%2Fnejm200003093421002&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216817240%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=xW5yFf020MDAZzeyQRqiskuGJ6XEflvlIN2pO9N26Uk%3D&reserved=0']invasive pneumococcal disease[/URL][/U]. The Parisian medical researchers wondered what could explain this. We knew at the time that the coronavirus binds to the ACE2 receptors expressed on the outside of cells in our airways, like a key fitting into a lock. But because COVID was often accompanied by an inflammatory component, it was hypothesized that the virus could [I]also[/I] bind to another type of receptor: nicotinic acetylcholine receptors or nAChRs for short. These receptors usually interact with the neurotransmitter acetylcholine, but molecules in some snake venoms and strains of the rabies virus can also bind to them because of a short sequence of amino acids. And this sequence was shared, the Parisian team found, by the spike protein that the coronavirus displayed at its surface like a crown of thorns. The new virus could thus, [I]in theory[/I], displace acetylcholine from nAChRs and cause damage. The hypothesis went on that, because nicotine binds to these same receptors very, very strongly, smokers were protected from the more severe effects of the coronavirus. The spike protein wanted to access this lock, but nicotine keys were already jammed in there and they were in no hurry to leave. Hence the otherwise unsound proposal, in the team’s April 2020 paper, that “nicotine may be suggested as a potential preventative agent against COVID-19 infection.” French doctors were not telling their countrymen to pick up a pack of Gauloises; they highlighted that nicotine is a “drug of abuse” and that smoking is bad, but they wondered about “nicotinic agents” in controlled settings. Perhaps nicotine patches. The scientific evidence for this hypothesis is, at this point, artificial and far from conclusive. A team has shown that, when [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.3390%2Fijms21165807&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216836362%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=EMEQ8CiinW1g4lhb5e7700iGLo9ViD%2F9yMmJS2St8aw%3D&reserved=0']using computers[/URL][/U] to predict what will happen, the coronavirus’ spike protein [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.fct.2021.112009&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216857317%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=BsLGv%2Bcha5Z6h3bT8TaSjlLuTIbcUjSUd4pRx%2Fn0Hk4%3D&reserved=0']can bind[/URL][/U] to these nicotinic receptors. Researchers have also forced cells in the lab (namely human kidney cells and frog egg cells) to express certain types of nicotinic receptors and put them in a solution containing a fragment of the spike protein created in the lab, and the [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1007%2Fs12035-022-02947-8&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216881283%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=aZ7wDKE%2F5Bfc3owOhj8OOrvNNCUsDGDr0yS2dJ4%2FwqI%3D&reserved=0']results[/URL][/U] [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1073%2Fpnas.2204242119&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216901595%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=%2BWV8FzZ1xW2H9EQSXLeuwhX%2FFWOas09VT9QEkUxxEPM%3D&reserved=0']have been[/URL][/U] [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.jbc.2023.104707&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216920808%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=wJHQSBJBN4WwbahF58HetA%2BS2MM7DDR8z7eDaFdWK%2BE%3D&reserved=0']contradictory[/URL][/U]. On either side of the debate, fans can pick the papers that support their position, but what the data reveals is that if this hypothesis is indeed true, it comes with a number of caveats. [COLOR=rgb(184, 49, 47)]Speaking of caveats, those early reports that smokers were underrepresented in COVID hospital wards were [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1038%2Fs41533-021-00223-1&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216940810%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=QWwngqTmc4YcGUPBJjgJ%2Flbq1dIVYSH3CpwDi8NFeQc%3D&reserved=0']deeply flawed[/URL][/U], using data sets where the smoking status of a significant portion of hospitalized patients was missing or where people who had recently stopped smoking were categorized not as smokers but as “former smokers.” Oh, and the French team that proposed the nicotinic hypothesis and suggested that maybe nicotine could prevent COVID-19? Its star scientist, Jean-Pierre Changeux, received [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.lemonde.fr%2Fsciences%2Farticle%2F2012%2F05%2F31%2Fguerre-du-tabac-la-bataille-de-la-nicotine_1710837_1650684.html&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635216963546%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=DfIApZFd5kGIvFZ%2BEfIWqj4k2WaDzrolfCwmzIQ0i1Y%3D&reserved=0']$220,000 from the tobacco industry[/URL][/U] to fund his research in the mid-90s, according to newspaper [/COLOR][I][COLOR=rgb(184, 49, 47)]Le Monde.[/COLOR] [COLOR=rgb(84, 172, 210)]Some people with long COVID report that nicotine patches [U][URL='https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fthesicktimes.org%2F2025%2F10%2F17%2Fnicotine-patches-help-relieve-symptoms-in-some-people-with-long-covid-can-the-science-behind-it-lead-to-future-therapies%2F&data=05%7C02%7Cangelina.lapalme%40mail.mcgill.ca%7C71f257b492534af57f3808de286a8a02%7Ccd31967152e74a68afa9fcf8f89f09ea%7C0%7C0%7C638992635217080665%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=bzQ74cCZWMiirbjXelDzMnpOj0N76WrHJzykrSN2N0U%3D&reserved=0']cleared their symptoms[/URL][/U], while others say their symptoms worsened. These anecdotes are not conclusive; rather, they can be hypothesis generating. In the absence of good, validated treatments for long COVID, I can understand the desire to try just about anything[/COLOR][/I] [/QUOTE]
Name
Verification
Post reply
Home
Sweatshop - Pure Drama
Political Fray
Kookie Kennedy to replace vaccine scientists from the vaccine advisory board, with essential oil sales representatives
