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Older adults who received the latest COVID-19 vaccine were significantly less likely to suffer serious heart-related complications, according to a major new study involving more than 1 million U.S. veterans.
The research, published in , found that people who received the 2024–2025 -19 had a lower risk of major adverse cardiovascular events—including heart attacks, strokes, heart failure hospitalizations and cardiovascular deaths—during the following eight months.
analyzed health records from more than 1 million veterans who received shots between September and December 2024.
Roughly one-third of the veterans also received a COVID-19 vaccine on the same day, allowing scientists to compare outcomes between vaccinated and unvaccinated groups.
The results were striking.
The researchers found a nearly 38% reduction in COVID-related cardiac events among the veterans—most notably among patients who were 75 or older, or who had other chronic conditions.
Interestingly, the showed that the vaccine had a secondary effect: It decreased all-cause cardiac events by 24%.
"While the reduction in COVID-19–associated [major adverse cardiovascular events] was modest, the substantially larger reduction in all-cause MACE suggests that the vaccine's protective association extends to the hidden burden of undetected SARS-CoV-2 and its sequelae," the researchers wrote in the study.
