I used to do a regular runs in the winter hauling produce from Nogales to Vancouver (1,771 miles/2,820 kilometers). That was probably one of the longer regular runs.
Calexico was also a popular destination for me too.
That part of the US, you don't even think you're in the US anymore... I got BEANED! I think I was the only White guy in town.
The Latina ladies were probably thinking, "Damn, what's that fine looking young White boy doing around here?" Unfortunately most of them couldn't speak English very well when you go into towns like that, so they couldn't express their thoughts and desires...